“This (disease) model suggests that the pathophysiology of Heat Stroke (HS) starts with a leaky gut, which results in the translocation of gram negative (thin-walled) bacteria from the gut into the intravascular space (within blood vessels)….Since the heat sepsis pathway originates from the leakage of gut-related LPS (Lipopolysaccharides – fat wrapped sugar molecule - emitted from dying bacteria), the prevention of Heat Stroke should include protecting the immune system, the integrity of the gut barrier, and the overall state of health, especially during periods of intense physical training and when immune functions and gut health can be compromised”, –